Skunks are often found in your yard, and they can transmit diseases to humans such as rabies. Skunks are primarily known for releasing the spray from their anal glands that cause intense discomfort if it gets into your eyes. Unfortunately, the skunk use this spray for self-defense this is why it is advisable that no one should try to remove them on their own. Here are listed the signs of skunks infestation that you can notice in your yard and immediately call the professionals for safe removal. Holes Skunks are natural burrower, and they often burrow and make holes in your garden, which is a significant sign of their presence..